gynecomastia

Breast diseases include various conditions and changes in your breast. Most women experience breast changes at some time. Your age, hormone levels, and medicines you take may cause lumps, bumps, and discharges of fluids that are not breast milk.

Although many women fear cancer, most breast changes are benign, meaning they are not cancer. These breast changes are known as benign breast disease. See your health care provider if you have a breast lump, pain, discharge, or skin irritation. Minor and serious breast problems often have similar symptoms and may need treatment.

Common breast changes and conditions can include:

• Fibrocystic breast changes can include lumpiness, thickening, and swelling, often just before your period. Your breasts may feel painful, swollen, or tender.
• Cysts are fluid-filled lumps that may be tender.
• Fibroadenomas are solid, round, rubbery lumps that easily move when pushed, occurring most in younger women.
• Intraductal papillomas are wart-like benign tumors that grow in the milk duct of the breast.
• Blocked milk ducts.
• Milk production when you're not breastfeeding.

Symptoms depend on the type of breast disease. Benign breast diseases may not have any symptoms, or they could include:

• A lump or firm feeling in your breast or under your arm
• A change in the size or shape of your breast
• Nipple discharge
• Skin changes such as itching, redness or darkening, dimples, scaling, or puckering on your breast or nipple
• Painful, swollen, or tender breasts

See your provider if you're noticing any of these symptoms or other unusual changes. Some symptoms may be warning signs or symptoms of breast cancer.

Some breast changes may be felt or seen. You may notice a change in your breast, or your provider may notice it during a clinical breast exam. Other breast changes may only be found during a screening mammogram or other imaging tests such as an MRI or ultrasound. Your provider may also recommend a breast biopsy to check a suspicious change in your breast.

Some benign breast changes may increase your risk of breast cancer in the future and may need treatment now. Treatment depends on the type of breast disease that you have. Some breast changes may go away without treatment, while others may require monitoring, biopsy, or surgery.

NIH: National Cancer Institute

Klinefelter syndrome (KS) is a genetic condition that happens when a male is born with an extra copy of the X chromosome. KS can affect different stages of physical, language, and social development. It also usually causes infertility.

KS is not inherited. It's caused by a random error that happens when a sperm or egg is formed. This error causes a male to be born with an extra X chromosome.

Chromosomes are tiny "packages" in your cells that contain your genes. Genes carry information, called DNA, that controls what you look like and how your body works. Normally, you're born with a set of 46 chromosomes in each cell, two of which are the sex chromosomes. Females usually have two X chromosomes (XX), and males usually have one X and one Y (XY). In KS, the male usually has two X chromosomes and one Y (XXY).

In rare cases, a male could have XY in some cells and XXY in other cells. This is called mosaic Klinefelter syndrome. Males with mosaic Klinefelter syndrome may have fewer symptoms, depending on the number of XY cells they have in their bodies and where those cells are located.

Some males with KS may have no symptoms or very mild symptoms. So they might not know that they have KS, or they might not get diagnosed with it right away. In other cases, the symptoms can be more severe.

Boys with KS may be taller than other boys their age, with more fat around the belly. After puberty, they may have:

• Smaller testes and penis
• Breast growth (called gynecomastia)
• Less facial and body hair
• Reduced muscle tone
• Narrower shoulders and wider hips
• Weaker bones
• Decreased sexual interest
• Lower energy

Many of these symptoms happen because of low testosterone in the body. Testosterone is the main male sex hormone.

Boys with KS may also have learning or language problems. These problems may affect them socially, so they may be shy and quiet and can have trouble fitting in.

Most males with KS are infertile because they make little or no sperm.

There is no cure for KS, but treatments are available. The sooner the treatment is started, the better. If treatment is started by early puberty, it will likely help in reducing the symptoms.

Treatments for KS may include:

• Testosterone replacement therapy
• Surgery to remove or reduce breasts
• Physical, speech, behavioral, and occupational therapy

In some cases, fertility treatments may help men with KS father children.

NIH: National Institute of Child Health and Human Development

Puberty is the time in life when a boy or girl becomes sexually mature. It is a process that usually happens between ages 10 and 14 for girls and ages 12 and 16 for boys. It causes physical changes, and affects boys and girls differently.

In girls:

• The first sign of puberty is usually breast development.
• Then hair grows in the pubic area and armpits.
• Menstruation (or a period) usually happens last.

In boys:

• Puberty usually begins with the testicles and penis getting bigger.
• Then hair grows in the pubic area and armpits.
• Muscles grow, the voice deepens, and facial hair develops as puberty continues.

Both boys and girls may get acne. They also usually have a growth spurt (a rapid increase in height) that lasts for about 2 or 3 years. This brings them closer to their adult height, which they reach after puberty.

NIH: National Institute of Child Health and Human Development

As a teenager, you go through many physical, mental, emotional, and social changes. The biggest change is puberty, the process of becoming sexually mature. It usually happens between ages 10 and 14 for girls and ages 12 and 16 for boys. As your body changes, you may have questions about sexual health.

During this time, you start to develop your own unique personality and opinions. Some changes that you might notice include:

• Increased independence from your parents
• More concerns about body image and clothes
• More influence from peers
• Greater ability to sense right and wrong

All of these changes can sometimes seem overwhelming. Some sadness or moodiness can be normal. But feeling very sad, hopeless, or worthless could be warning signs of a mental health problem. If you need help, talk to your parents, school counselor, or health care provider.

Centers for Disease Control and Prevention