| Medical Dictionary |
A Medical Dictionary of Medical Terminology
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The chest is the part of your body between your neck and your abdomen (belly). The medical term for your chest is thorax.
Your chest holds many important structures for breathing, digestion, blood circulation, and other important body functions. These structures include your:
Chest injuries and disorders are problems that affect any of the organs or structures located in your chest.
There are many types of chest injuries and disorders, for example:
Chest injuries may happen from the force of car accidents, falls, or sports injuries. Or the chest may be pierced by a bullet or sharp object. Because your chest holds so many important structures, certain chest injuries may be life-threatening.
How are chest injuries and disorders diagnosed?Diagnosis of chest injuries or disorders depends on the type of symptoms you're having and whether you've had a chest injury. Injuries are usually obvious, but in most cases, you'll need tests to know how serious an injury is.
There are many types of tests for diagnosing different types of chest injuries and disorders, for example:
Treatments will depend on the type of chest injury or disorder you have.
Leukemia is a term for cancers of the blood cells. Leukemia starts in blood-forming tissues such as the bone marrow. Your bone marrow makes the cells which will develop into white blood cells, red blood cells, and platelets. Each type of cell has a different job:
When you have leukemia, your bone marrow makes large numbers of abnormal cells. This problem most often happens with white blood cells. These abnormal cells build up in your bone marrow and blood. They crowd out the healthy blood cells and make it hard for your cells and blood to do their work.
What is acute lymphocytic leukemia (ALL)?Acute lymphocytic leukemia is a type of acute leukemia. It's also called ALL and acute lymphoblastic leukemia. "Acute" means that it usually gets worse quickly if it's not treated. ALL is the most common type of cancer in children. It can also affect adults.
In ALL, the bone marrow makes too many lymphocytes, a type of white blood cell. These cells normally help your body fight infection. But in ALL, they are abnormal and cannot fight infection very well. They also crowd out the healthy cells, which can lead to infection, anemia, and easy bleeding. These abnormal cells can also spread to other parts of the body, including the brain and spinal cord.
What causes acute lymphocytic leukemia (ALL)?ALL happens when there are changes in the genetic material (DNA) in bone marrow cells. The cause of these genetic changes is unknown. However, there are certain factors that raise your risk of ALL.
Who is at risk for acute lymphocytic leukemia (ALL)?The factors that raise your risk of ALL include:
The signs and symptoms of ALL include:
Your health care provider may use many tools to diagnose ALL and figure out which subtype you have:
If you are diagnosed with ALL, you may have additional tests to see whether the cancer has spread. These include imaging tests and a lumbar puncture, which is a procedure to collect and test cerebrospinal fluid (CSF).
What are the treatments for acute lymphocytic leukemia (ALL)?Treatments for ALL include:
Treatment is usually done in two phases:
Treatment during both phases also usually includes central nervous system (CNS) prophylaxis therapy. This therapy helps prevent the spread of leukemia cells to the brain and spinal cord. It may be high dose chemotherapy or chemotherapy injected into the spinal cord. It also sometimes includes radiation therapy.
NIH: National Cancer Institute
A bone graft transplants bone tissue. Surgeons use bone grafts to repair and rebuild diseased bones in your hips, knees, spine, and sometimes other bones and joints. Grafts can also repair bone loss caused by some types of fractures (broken bones) or cancers. Once your body accepts the bone graft, it provides a framework for growth of new, living bone.
If the transplanted bone comes from another person, it is called an allograft. Most allograft bone comes from donors who have died. Tissue banks screen these donors and disinfect and test the donated bone to make sure it is safe to use. If the transplanted bone comes from another part of your own body, it is called an autograft. Autograft bone often comes from your ribs, hips or a leg.
Leukemia is a term for cancers of the blood cells. Leukemia starts in blood-forming tissues such as the bone marrow. Your bone marrow makes the cells which will develop into white blood cells, red blood cells, and platelets. Each type of cell has a different job:
When you have leukemia, your bone marrow makes large numbers of abnormal cells. This problem most often happens with white blood cells. These abnormal cells build up in your bone marrow and blood. They crowd out the healthy blood cells and make it hard for your cells and blood to do their work.
What is chronic lymphocytic leukemia (CLL)?Chronic lymphocytic leukemia (CLL) is a type of chronic leukemia. "Chronic" means that the leukemia usually gets worse slowly. In CLL, the bone marrow makes abnormal lymphocytes (a type of white blood cell). When the abnormal cells crowd out the healthy cells, it can lead to infection, anemia, and easy bleeding. The abnormal cells can also spread outside the blood to other parts of the body. CLL is one of the most common types of leukemia in adults. It often occurs during or after middle age. It is rare in children.
What causes chronic lymphocytic leukemia (CLL)?CLL happens when there are changes in the genetic material (DNA) in bone marrow cells. The cause of these genetic changes is unknown, so it's hard to predict who might get CLL. There are a few factors that might raise your risk.
Who is at risk for chronic lymphocytic leukemia (CLL)?It is hard to predict who will get CLL. There are a few factors that could raise your risk:
In the beginning, CLL does not cause any symptoms. Later, you can have symptoms such as:
Your health care provider may use many tools to diagnose CLL:
If you are diagnosed with CLL, you may have additional tests to see whether the cancer has spread. These include imaging tests and bone marrow tests.
What are the treatments for chronic lymphocytic leukemia (CLL)?Treatments for CLL include:
The goals of treatment are to slow the growth of the leukemia cells and to give you long periods of remission. Remission means that the signs and symptoms of cancer are reduced or have disappeared. The CLL may come back after remission, and you may need more treatment.
NIH: National Cancer Institute
Leukemia is a term for cancers of the blood cells. Leukemia starts in blood-forming tissues such as the bone marrow. Your bone marrow makes the cells which will develop into white blood cells, red blood cells, and platelets. Each type of cell has a different job:
When you have leukemia, your bone marrow makes large numbers of abnormal cells. This problem most often happens with white blood cells. These abnormal cells build up in your bone marrow and blood. They crowd out the healthy blood cells and make it hard for your cells and blood to do their work.
What is chronic myeloid leukemia (CML)?Chronic myeloid leukemia (CML) is a type of chronic leukemia. "Chronic" means that the leukemia usually gets worse slowly. In CML, the bone marrow makes abnormal granulocytes (a type of white blood cell). These abnormal cells are also called blasts. When the abnormal cells crowd out the healthy cells, it can lead to infection, anemia, and easy bleeding. The abnormal cells can also spread outside the blood to other parts of the body.
CML usually occurs in adults during or after middle age. It is rare in children.
What causes chronic myeloid leukemia (CML)?Most people with CML have a genetic change called the Philadelphia chromosome. It's called that because researchers in Philadelphia discovered it. People normally have 23 pairs of chromosomes in each cell. These chromosomes contain your DNA (genetic material). In CML, part of the DNA from one chromosome moves to another chromosome. It combines with some DNA there, which creates a new gene called BCR-ABL. This gene causes your bone marrow to make an abnormal protein. This protein allows the leukemia cells to grow out of control.
The Philadelphia chromosome isn't passed from parent to child. It happens during your lifetime. The cause is unknown.
Who is at risk for chronic myeloid leukemia (CML)?It is hard to predict who will get CML. There are a few factors that could raise your risk:
Sometimes CML does not cause symptoms. If you do have symptoms, they can include:
Your health care provider may use many tools to diagnose CML:
If you are diagnosed with CML, you may have additional tests such as imaging tests to see whether the cancer has spread.
What are the phases of chronic myeloid leukemia (CML)?CML has three phases. The phases are based on how much the CML has grown or spread:
There are several different treatments for CML:
Which treatments you get will depend on which phase you are in, your age, your overall health, and other factors. When the signs and symptoms of CML are reduced or have disappeared, it is called remission. The CML may come back after remission, and you may need more treatment.
NIH: National Cancer Institute
Heart surgery can correct certain heart problems when other treatments haven't worked or can't be used.
In some cases, heart surgery may be a medical emergency. For example, surgery for a severe heart attack may need to be done right away. In other cases, you can plan heart surgery ahead of time. Some heart surgeries are major operations, such as heart bypass surgery for blocked arteries in the heart. Other surgeries are more minor heart procedures, such as putting in a pacemaker.
What conditions does heart surgery treat?There are different types of heart surgery that can help treat many heart conditions:
What conditions does heart surgery treat?What does the heart surgery do?Coronary artery disease (CAD) - when a sticky substance called plaque narrows or blocks the arteries that supply blood to your heart muscle.Makes a new path for blood to flow around the blocked part of an artery in the heart. This is called a coronary artery bypass graft (CABG), or heart bypass. It's the most common heart surgery in adults.Heart valve diseases - problems with the valves that control the flow of blood through your heart.Repairs heart valves.Replaces heart valves with a mechanical valve or a biologic valve made from pig, cow, or human heart tissue.Arrhythmia - problems with the rate or rhythm of your heartbeat. They are caused by changes in the electrical signals that control your heartbeat.Places a pacemaker or an implantable cardioverter defibrillator (ICD) in the chest to correct your heartbeat.Treats atrial fibrillation with small cuts in the heart muscle. The cuts form scars that make a path for the heart's electrical signals (Maze surgery).Heart failure - when your heart is too weak or stiff to pump enough oxygen-rich blood to meet your body's needs.Places a device in the chest which may include:The approach a surgeon uses to do heart surgery depends on your heart problem, your general health, and other factors. Approaches to heart surgery include:
Like all surgery, heart surgery has risks even though the results are often excellent. The risks include:
The risks of heart surgery tend to be higher if:
NIH: National Heart, Lung, and Blood Institute
You have two kidneys, each about the size of your fist. They are near the middle of your back, just below the rib cage. Inside each kidney there are about a million tiny structures called nephrons. They filter your blood. They remove wastes and extra water, which become urine. The urine flows through tubes called ureters. It goes to your bladder, which stores the urine until you go to the bathroom.
Most kidney diseases attack the nephrons. This damage may leave kidneys unable to remove wastes. Causes can include genetic problems, injuries, or medicines. You have a higher risk of kidney disease if you have diabetes, high blood pressure, or a close family member with kidney disease. Chronic kidney disease damages the nephrons slowly over several years. Other kidney problems include:
Your doctor can do blood and urine tests to check if you have kidney disease. If your kidneys fail, you will need dialysis or a kidney transplant.
NIH: National Institute of Diabetes and Digestive and Kidney Diseases
The tissue that lines your lungs, stomach, heart, and other organs is called mesothelium. Mesothelioma, also known as malignant mesothelioma, is cancer of that tissue. It usually starts in the lungs, but can also start in the abdomen or other organs.
Malignant mesothelioma is rare but serious. Most people who get it have worked or lived in places where they inhaled or swallowed asbestos particles. After being exposed to asbestos, it usually takes a long time for the disease to form.
Symptoms include:
Sometimes it is hard to tell the difference between malignant mesothelioma and lung cancer. To find out if you have mesothelioma, your health care provider will likely use a physical exam, imaging tests, and a biopsy.
Malignant mesothelioma is often found when it is advanced. This makes it harder to treat. Treatment options may include:
NIH: National Cancer Institute
Multiple myeloma is a cancer that begins in plasma cells, a type of white blood cell. These cells are part of your immune system, which helps protect the body from germs and other harmful substances. In time, myeloma cells collect in the bone marrow and in the solid parts of bones.
No one knows the exact causes of multiple myeloma, but it is more common in older people and African Americans. It can run in families. Common symptoms may include:
Doctors diagnose multiple myeloma using lab tests, imaging tests, and a bone marrow biopsy. Your treatment depends on how advanced the disease is and whether you have symptoms. If you have no symptoms, you may not need treatment right away. If you have symptoms, you may have chemotherapy, stem cell transplantation, radiation, or targeted therapy. Targeted therapy uses drugs or other substances that attack specific cancer cells with less harm to normal cells.
NIH: National Cancer Institute
Respiratory failure is a condition in which your blood doesn't have enough oxygen or has too much carbon dioxide. Sometimes you can have both problems.
When you breathe, your lungs take in oxygen. The oxygen passes into your blood, which carries it to your organs. Your organs, such as your heart and brain, need this oxygen-rich blood to work well.
Another part of breathing is removing the carbon dioxide from the blood and breathing it out. Having too much carbon dioxide in your blood can harm your organs.
What causes respiratory failure?Conditions that affect your breathing can cause respiratory failure. These conditions may affect the muscles, nerves, bones, or tissues that support breathing. Or they may affect the lungs directly. These conditions include:
The symptoms of respiratory failure depend on the cause and the levels of oxygen and carbon dioxide in your blood.
A low oxygen level in the blood can cause shortness of breath and air hunger (the feeling that you can't breathe in enough air). Your skin, lips, and fingernails may also have a bluish color. A high carbon dioxide level can cause rapid breathing and confusion.
Some people who have respiratory failure may become very sleepy or lose consciousness. They also may have arrhythmia (irregular heartbeat). You may have these symptoms if your brain and heart are not getting enough oxygen.
How is respiratory failure diagnosed?Your health care provider will diagnose respiratory failure based on:
Once you are diagnosed with respiratory failure, your provider will look for what is causing it. Tests for this often include a chest x-ray. If your provider thinks you may have arrhythmia because of the respiratory failure, you may have an EKG (electrocardiogram). This is simple, painless test that detects and records your heart's electrical activity.
What are the treatments for respiratory failure?Treatment for respiratory failure depends on:
Acute respiratory failure can be a medical emergency. You may need treatment in intensive care unit at a hospital. Chronic respiratory failure can often be treated at home. But if your chronic respiratory failure is severe, you might need treatment in a long-term care center.
One of the main goals of treatment is to get oxygen to your lungs and other organs and remove carbon dioxide from your body. Another goal is to treat the cause of the condition. Treatments may include:
If you have respiratory failure, see your health care provider for ongoing medical care. Your provider may suggest pulmonary rehabilitation.
If your respiratory failure is chronic, make sure that you know when and where to get help for your symptoms. You need emergency care if you have severe symptoms, such as trouble catching your breath or talking. You should call your provider if you notice that your symptoms are worsening or if you have new signs and symptoms.
Living with respiratory failure may cause fear, anxiety, depression, and stress. Talk therapy, medicines, and support groups can help you feel better.
NIH: National Heart, Lung, and Blood Institute