gynecomastia

Most women experience breast changes at some time. Your age, hormone levels, and medicines you take may cause lumps, bumps, and discharges (fluids that are not breast milk).

If you have a breast lump, pain, discharge or skin irritation, see your health care provider. Minor and serious breast problems have similar symptoms. Although many women fear cancer, most breast problems are not cancer.

Some common breast changes are:

• Fibrocystic breast changes - lumpiness, thickening and swelling, often just before a woman's period
• Cysts - fluid-filled lumps
• Fibroadenomas - solid, round, rubbery lumps that move easily when pushed, occurring most in younger women
• Intraductal papillomas - growths similar to warts near the nipple
• Blocked milk ducts
• Milk production when a woman is not breastfeeding

NIH: National Cancer Institute

Klinefelter syndrome (KS) is a genetic condition that happens when a male is born with an extra copy of the X chromosome. KS can affect different stages of physical, language, and social development. It also usually causes infertility.

KS is not inherited. It's caused by a random error that happens when a sperm or egg is formed. This error causes a male to be born with an extra X chromosome.

Chromosomes are tiny "packages" in your cells that contain your genes. Genes carry information, called DNA, that controls what you look like and how your body works. Normally, you're born with a set of 46 chromosomes in each cell, two of which are the sex chromosomes. Females usually have two X chromosomes (XX), and males usually have one X and one Y (XY). In KS, the male usually has two X chromosomes and one Y (XXY).

In rare cases, a male could have XY in some cells and XXY in other cells. This is called mosaic Klinefelter syndrome. Males with mosaic Klinefelter syndrome may have fewer symptoms, depending on the number of XY cells they have in their bodies and where those cells are located.

Some males with KS may have no symptoms or very mild symptoms. So they might not know that they have KS, or they might not get diagnosed with it right away. In other cases, the symptoms can be more severe.

Boys with KS may be taller than other boys their age, with more fat around the belly. After puberty, they may have:

• Smaller testes and penis
• Breast growth (called gynecomastia)
• Less facial and body hair
• Reduced muscle tone
• Narrower shoulders and wider hips
• Weaker bones
• Decreased sexual interest
• Lower energy

Many of these symptoms happen because of low testosterone in the body. Testosterone is the main male sex hormone.

Boys with KS may also have learning or language problems. These problems may affect them socially, so they may be shy and quiet and can have trouble fitting in.

Most males with KS are infertile because they make little or no sperm.

There is no cure for KS, but treatments are available. The sooner the treatment is started, the better. If treatment is started by early puberty, it will likely help in reducing the symptoms.

Treatments for KS may include:

• Testosterone replacement therapy
• Surgery to remove or reduce breasts
• Physical, speech, behavioral, and occupational therapy

In some cases, fertility treatments may help men with KS father children.

NIH: National Institute of Child Health and Human Development

Puberty is the time in life when a boy or girl becomes sexually mature. It is a process that usually happens between ages 10 and 14 for girls and ages 12 and 16 for boys. It causes physical changes, and affects boys and girls differently.

In girls:

• The first sign of puberty is usually breast development.
• Then hair grows in the pubic area and armpits.
• Menstruation (or a period) usually happens last.

In boys:

• Puberty usually begins with the testicles and penis getting bigger.
• Then hair grows in the pubic area and armpits.
• Muscles grow, the voice deepens, and facial hair develops as puberty continues.

Both boys and girls may get acne. They also usually have a growth spurt (a rapid increase in height) that lasts for about 2 or 3 years. This brings them closer to their adult height, which they reach after puberty.

NIH: National Institute of Child Health and Human Development

As a teenager, you go through many physical, mental, emotional, and social changes. The biggest change is puberty, the process of becoming sexually mature. It usually happens between ages 10 and 14 for girls and ages 12 and 16 for boys. As your body changes, you may have questions about sexual health.

During this time, you start to develop your own unique personality and opinions. Some changes that you might notice include:

• Increased independence from your parents
• More concerns about body image and clothes
• More influence from peers
• Greater ability to sense right and wrong

All of these changes can sometimes seem overwhelming. Some sadness or moodiness can be normal. But feeling very sad, hopeless, or worthless could be warning signs of a mental health problem. If you need help, talk to your parents, school counselor, or health care provider.

Centers for Disease Control and Prevention