pseudomembranous

C. diff is a bacterium that can cause diarrhea and more serious intestinal conditions such as colitis. You may see it called other names, such as Clostridioides difficile (the new name), Clostridium difficile (an older name), and C. difficile. It causes close to half a million illnesses each year.

C. diff bacteria are commonly found in the environment, but people usually only get C. diff infections when they are taking antibiotics. That's because antibiotics not only wipe out bad germs, but they also kill the good germs that protect your body against infections. The effect of antibiotics can last as long as several months. If you come in contact with C. diff germs during this time, you can get sick. You are more likely to get a C. diff infection if you take antibiotics for more than a week.

C. diff spreads when people touch food, surfaces, or objects that are contaminated with feces (poop) from a person who has C. diff.

You are at more likely to get a C. diff infection if you:

• Are taking antibiotics
• Are 65 or older
• Recently stayed in a hospital or nursing home
• Have a weakened immune system
• Have had a previous infection with C. diff or were exposed to it

The symptoms of C. diff infections include:

• Diarrhea (loose, watery stools) or frequent bowel movements for several days
• Fever
• Stomach tenderness or pain
• Loss of appetite
• Nausea

Severe diarrhea causes you to lose a lot of fluids. This can put you at risk for dehydration.

If you have been taking antibiotics recently and have symptoms of a C. diff infection, you should see your health care provider. Your provider will ask about your symptoms and do a lab test of your stool. In some cases, you might also need an imaging test such as an x-ray or CT scan to check for complications.

Certain antibiotics can treat C. diff infections. If you were already taking a different antibiotic when you got C. diff, your provider may ask you to stop taking that one.

If you have a severe case, you may need to stay in the hospital. If you have very severe pain or serious complications, you may need surgery to remove the diseased part of your colon.

About 1 in 6 people who have had a C. diff infection will get it again within the following 2 to 8 weeks. This is called recurrent C. diff. It could be that your original infection came back or that you have a new infection. Contact your provider if your symptoms come back.

For people who keep getting C. diff infections, treatments such as fecal microbiota transplants (FMT) have shown promising results. FMT uses stool (or bacteria from stool) from a healthy donor to try to restore the balance of healthy bacteria in your intestines.

There are steps you can take to try to prevent getting or spreading C. diff:

• Wash your hands with soap and water after you use the bathroom and before you eat.
• If you have diarrhea, clean the bathroom that you used before anyone else uses it. Use bleach mixed with water or another disinfectant to clean the toilet seat, handle, and lid.

Health care providers can also help prevent C. diff infections by taking infection control precautions and improving how they prescribe antibiotics.

Centers for Disease Control and Prevention

Antibiotics are medicines that fight bacterial infections in people and animals. They work by killing the bacteria or by making it hard for the bacteria to grow and multiply.

Antibiotics can be taken in different ways:

• Orally (by mouth). This could be pills, capsules, or liquids.
• Topically. This might be a cream, spray, or ointment that you put on your skin. It could also be eye ointment, eye drops, or ear drops.
• Through an injection or intravenously (IV). This is usually for more serious infections.

Antibiotics only treat certain bacterial infections, such as strep throat, urinary tract infections, and E. coli.

You may not need to take antibiotics for some bacterial infections. For example, you might not need them for many sinus infections or some ear infections. Taking antibiotics when they're not needed won't help you, and they can have side effects. Your health care provider can decide the best treatment for you when you're sick. Don't ask your provider to prescribe an antibiotic for you.

Antibiotics do not work on viral infections. For example, you shouldn't take antibiotics for:

• Colds and runny noses, even if the mucus is thick, yellow, or green
• Most sore throats (except strep throat)
• Flu
• Most cases of bronchitis

The side effects of antibiotics range from minor to very severe. Some of the common side effects include:

• Rash
• Nausea
• Diarrhea
• Yeast infections

More serious side effects can include:

• C. diff infections, which cause diarrhea that can lead to severe colon damage and sometimes even death
• Severe and life-threatening allergic reactions
• Antibiotic resistance infections

Call your health care provider if you develop any side effects while taking your antibiotic.

You should only take antibiotics when they are needed because they can cause side effects and can contribute to antibiotic resistance. Antibiotic resistance happens when the bacteria change and become able to resist the effects of an antibiotic. This means that the bacteria continue to grow.

When you take antibiotics, it is important that you take them responsibly:

• Always follow the directions carefully. Finish your medicine even if you feel better. If you stop taking them too soon, some bacteria may survive and re-infect you.
• Don't save your antibiotics for later.
• Don't share your antibiotic with others.
• Don't take antibiotics prescribed for someone else. This may delay the best treatment for you, make you even sicker, or cause side effects.

Centers for Disease Control and Prevention